Spay/Neuter Clinic

Specials & Coupons >>

Spay/Neuter Clinic Hours:

  • OPEN: Monday–Friday by Appointment
    • Surgery Drop off: 7:30AM – 9:00AM
    • Surgery Pick up: 4:30PM – 5:30PM
  • CLOSED: Saturday & Sunday
    *All calls & emails received after 6:00PM will be returned the following business day.

Schedule An Appointment (Email preferred*):

*EMAIL      -OR-      CALL  (864)242-3626 Ext. 232

Be sure to:
Print and fill out the attached forms. Bring 2 copies of each completed form to the Clinic with your pet for surgery.

  • Microchip Registration Form (if bringing in your pet for microchip implantation)
  • Surgery Release Form
  • Surgery Waiver Form (for pets 6 years and older)
  • Provide current vaccine records (Rabies & Distemper vaccines required for surgery). If you cannot provide proof of these vaccinations, they will be administered at the time of surgery for $7 each. To see a list of other services available during the time of surgery, please click here.*

Please read post-operation information: PostOpHighlights.pdf

Spay/Neuter Surgery Prices**

Specials & Coupons >>

Dogs (8-16 weeks of age):
Female $49
Male $39

Dogs (Over 16 weeks of age and less than 25 lbs.):
Female $59
Male $49

Dogs (Over 25 lbs.):
Female $79
Male $59

Cats and Kittens (Must be at least 2 lbs. and 8 weeks of age):
Female $49
Male  $29 ($10 on Tom Cat Tuesday)

* We require your pet be up to date on the following vaccines: Rabies (for animals 12 weeks of age & older) and Distemper (DA2PPV/FVRCP). If you cannot provide proof of these vaccinations, they will be administered at the time of surgery for $7 each. To see a list of other services available during the time of surgery, please click here.

** Additional charges will apply to animals that are pregnant, in heat, obese, possess undescended testicles, or have other conditions that will increase surgery time.

Tom Cat Tuesday

Male cat neuters are only $10 every Tuesday! Appointment required. To schedule a surgery appointment call (864)242-3626 x232 or send an email to

Spay/Neuter Clinic Facts

  • The Greenville Humane Society Spay/Neuter Clinic has been in operation for 30 years, the oldest clinic in the community.
  • We operate a state-of-the-art clinic, and economical vaccine and testing services.
  • We have specialized veterinarians with exceptional surgical skills.
  • While our clinic performs thousands of spay/neuter surgeries each year, we still find time to offer personal attention to every animal!

Benefits of Pediatric Spay/Neuter (8-16 weeks of age):

  • Less physiologically stressful on younger patients; the surgery is faster and easier on younger patients.
  • Pediatric surgery is less expensive because of the use of fewer materials, and because less staff time is needed for surgery and pre and postoperative preparation and monitoring.
  • There are fewer complications associated with pediatric spay/neuter than with spay/neuter performed at an older age.
  • Spaying an animal before the first heat prevents the development of mammary gland tumors later in life. Since kittens may go into heat at 4 months of age, waiting until 6 months risks accidental pregnancy and loses the protection against mammary gland cancer.
  • Pyometra is a potentially life-threatening condition whose incidence approaches 66% in older unspayed females. It can be very expensive to treat but it is easily prevented by pediatric spaying.
  • Reduces the urge of male animals to spray urine to mark territory, and to roam and fight with other male animals.
  • Prevents accidental pregnancies. The delay in neutering pets is often responsible for the production of accidental litters that end up at shelters.
  • Studies have shown that intact animals are much more likely to be relinquished to shelters than sterilized ones. Pediatric spay/neuter is an essential component of a comprehensive community strategy to end the euthanasia of unwanted companion animals in the United States.

How do we keep our spay/neuter costs so much lower?

Volume! We perform nearly 10,000 spay and neuter surgeries each year.  Unlike a private practice vet office who may perform a handful per day, we can spay/neuter 30-60 (or more!) every day, 5 days a week.  We utilize the same quality materials, licensed veterinarians, and anesthetic protocols that you would expect from your family veterinarian. But, unlike your family veterinarian, we are not a full service practice; we do not treat illnesses or provide medical care, other than routine vaccinations.

We have specialized surgeons

We have highly-trained veterinarians that specialize in performing spays and neuters.  Many of the veterinarians that work here at the Greenville Humane Society also work in private practice, they are so passionate about ending animal overpopulation that they spend a few days a week doing spays/neuters at our shelter.  Our skilled veterinarians have undergone special training to enable them to perform spays and neuters faster, and with fewer complications.

We are a non-profit organization

We are here solely for our community and the animals.  All of the money that we receive for our services goes directly back to care for the animals we serve.  We keep our cost to you as low as possible while providing excellent service and care for your animals. We treat your animals as if they were our own.

Low Cost Vaccine Clinic

In addition to spay/neuter surgery, the Greenville Humane Society provides a low-cost vaccination clinic.

View our Vaccine Prices »